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TRYPTOPHAN OXYGENASE
Descriptors Found:
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DeCS
Descriptor
English
:
Tryptophan Oxygenase
Descriptor
Spanish
:
Triptófano Oxigenasa
Descriptor
Portuguese
:
Triptofano Oxigenase
Synonyms
English
:
2,3-Dioxygenase, Tryptophan
Dioxygenase, TDO
Oxygenase, Tryptophan
Pyrrolase, Tryptophan
TDO Dioxygenase
Tryptophan 2,3 Dioxygenase
Tryptophan 2,3-Dioxygenase
Tryptophan Pyrrolase
Tree Number:
D08.811.682.690.416.722
Definition
English
:
A dioxygenase with specificity for the
oxidation
of the indoleamine ring of
TRYPTOPHAN
. It is a LIVER-specific enzyme that is the first and rate limiting enzyme in the
kynurenine
pathway of
TRYPTOPHAN
catabolism.
See Related
English
:
Tryptophan Hydroxylase
History Note
English
:
68(65)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
14768
Unique Identifier:
D014366
Occurrence in VHL
:
Similar:
DeCS